Displacement and loss of livelihoods: The project requires the acquisition of approximately 257 acres of land used by communities for growing and harvesting crops. In July 2015, ENI estimated in their Final Environmental Impact Statement that around 213 acres of farmland could become inaccessible to 180 farmers of the Sanzule community.. Fishermen in the region have reported a severe decline in catch predominantly due to the artificial lighting system of vessels which attract fish to the oil and gas fields. They report that several fish species have become extinct in the region. The fishermen are also restricted by a no-fishing zone 500m around the premises of the project and their boats are seized by police if they enter this zone.

Complaints have also been made about several fish species going extinct. Most of the time, the nets used by fishermen are full of seaweed and no fish. This is a direct consequence of drilling in the region, which cuts seaweed. All these factors have led to considerable losses for fishermen, which in turn has consequences for their economic stability. 

Increased cost of living: With the construction of new power plants in the region, more people have migrated to the area looking for employment. This has led to a substantial increase in market prices and rent costs, thereby making life even harder for the communities that have lost their livelihoods.

Air pollution: Construction activities lead to emissions in the form of nitrous oxide, carbon dioxide, sulphur dioxide and particulate matter. These emissions are particularly attributed to earth moving, excavation and transportation activities. Air pollution will also be a result of the operation of the FPSO, since it uses turbines and fuel for power generation. 

Impacts on marine ecology: This project  is predominantly set on the seabed. The pipelines, drilling activities and the operation of vessels have the potential to cause seawater turbidity and will also lead to seeping of contaminants such as zinc and arsenic into the seawater. This impacts marine life and in turn also impacts the livelihoods of fishermen.

Climate change: The OCTP contributes to an increase in greenhouse gas emissions.The emissions from the OCTP project originate from operations for well completions (power generation exhaust emissions); FPSO operations (power generation exhaust emissions and non-routine flaring); marine support vessels and helicopters (power generation exhaust emissions); and filling, offloading and operation of export tankers (exhaust and fugitive emissions).
Climate change is manifested in Ghana through: rising temperatures, declining rainfall totals and increased variability, rising sea levels and high incidence of weather extremes and disasters, such as floods. More than 30 years of climate records show that the prevailing climatic conditions in Ghana have severely deteriorated and are likely to worsen in the future. Climate forecast and climate change scenarios for the country predict a more severe and frequent pattern of droughts and flood events. Ghana is particularly vulnerable due to its reliance on sectors that are sensitive to these impacts, such as agriculture, forestry and energy production.

Decreasing value of Ghana’s energy sector: Most of Ghana's LNG and energy projects have been contracted without accurate estimates for future demand. Ghana's oil and gas sector is not stable as many factors threaten the future of the industry. Some major issues come from low non-power demand, the procurement of LNG without a long-term plan and also large financial exposure to Take-or-Pay contracts. As a consequence, there is an excess of supply that is underpriced and therefore leads to a rapid rise in debts. The excess in the supply of gas leads to a considerable drop in the price of gas. Aditionally, due to the  take-or-pay contracts, Ghana National Petroleum Corporation (GNPC) has to pay the private sector for supplies they cannot sell. This amounted to over USD 168 million in 2019.